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Clinical trials for Renal Failure

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43871   clinical trials with a EudraCT protocol, of which   7290   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    1,888 result(s) found for: Renal Failure. Displaying page 1 of 95.
    1  2  3  4  5  6  7  8  9  Next» Last»»
    EudraCT Number: 2010-022994-32 Sponsor Protocol Number: 34009 Start Date*: 2011-06-24
    Sponsor Name:UMC Utrecht
    Full Title: Effect of N-acetylcysteine on hydrogen sulfide in chronic kidney disease
    Medical condition: Chronic kidney disease End stage renal disease
    Disease: Version SOC Term Classification Code Term Level
    12.1 10064848 Chronic kidney disease LLT
    12.1 10014646 End stage renal disease (ESRD) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-008246-20 Sponsor Protocol Number: ABR 25995 Start Date*: Information not available in EudraCT
    Sponsor Name:Radboud University Nijmegen Medical Center, Department of Anaesthesiology, Pain and Palliative Medic
    Full Title: Evaluation of the efficacy and safety of sugammadex (Bridion) in children with renal failure.
    Medical condition: Sugammadex is a selective relaxant binding agent, which is administered in case of a rocuronium-induced neuromuscular block, during general anaesthesia. The aim of the trial is to investigate the u...
    Disease: Version SOC Term Classification Code Term Level
    9.1 10038443 Renal failure and impairment HLT
    9.1 10009119 Chronic renal failure LLT
    9.1 10014647 End stage renal failure LLT
    Population Age: Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: NL (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2014-001296-32 Sponsor Protocol Number: FC/HULP-2014_01 Start Date*: 2014-07-07
    Sponsor Name:Fundación para la Investigación Biomédica del Hospital Universitario de La Paz
    Full Title: Pharmacokinetic and pharmacodynamic optimization of amikacin treatment in patients with terminal renal failure under conventional hemodialysis: randomized clinical trial of two model of administration
    Medical condition: Terminal renal failure under hemodialysis
    Disease: Version SOC Term Classification Code Term Level
    17.0 10038359 - Renal and urinary disorders 10038444 Renal failure chronic PT
    17.0 10038359 - Renal and urinary disorders 10014647 End stage renal failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2013-002267-25 Sponsor Protocol Number: PIVOTAL Start Date*: 2013-09-06
    Sponsor Name:King's College Hospital NHS Foundation Trust
    Full Title: UK Multicentre Open-label Randomised Controlled Trial Of IV Iron Therapy In Incident Haemodialysis Patients
    Medical condition: Iron-deficiency in anaemia of end stage renal disease.
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004857 10064848 Chronic kidney disease LLT
    16.0 100000004851 10066763 Chronic iron deficiency anaemia LLT
    16.0 100000004865 10066623 Chronic haemodialysis LLT
    16.0 100000004857 10014647 End stage renal failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: View results
    EudraCT Number: 2021-000894-94 Sponsor Protocol Number: KOR-PED-201 Start Date*: 2021-08-26
    Sponsor Name:Vifor Fresenius Medical Care Renal Pharma Ltd.
    Full Title: An Open-label, Single Arm Study to Evaluate the Pharmacokinetics of a Single Dose of Intravenous Difelikefalin in Adolescents Aged 12 to 17 Years on Haemodialysis
    Medical condition: Renal disease in the final stage
    Disease: Version SOC Term Classification Code Term Level
    21.1 10038359 - Renal and urinary disorders 10014646 End stage renal disease (ESRD) LLT
    21.0 10038359 - Renal and urinary disorders 10077512 End stage renal disease PT
    Population Age: Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-018838-45 Sponsor Protocol Number: RLY5016–204 Start Date*: 2010-04-21
    Sponsor Name:Relypsa, Inc.
    Full Title: A Multicenter, Open-Label, Single-Arm Study to Evaluate a Titration Regimen for RLY5016 in Heart Failure Patients with Chronic Kidney Disease
    Medical condition: Heart failure with Chronic kidney disease
    Disease: Version SOC Term Classification Code Term Level
    12.1 10008908 Chronic heart failure LLT
    12.1 10064848 Chronic kidney disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SI (Completed)
    Trial results: View results
    EudraCT Number: 2011-002586-38 Sponsor Protocol Number: RPH-1101 Start Date*: 2011-10-14
    Sponsor Name:Renapharma AB
    Full Title: A 12-week clinical double-blind, randomised study of cholecalciferol versus placebo in patients with chronic kidney disease stage 3-4 (CHICK).
    Medical condition: Chronic renal failure, stage 3-4
    Disease: Version SOC Term Classification Code Term Level
    14.0 10038359 - Renal and urinary disorders 10038444 Renal failure chronic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: SE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2017-002450-37 Sponsor Protocol Number: IOEX2017 Start Date*: 2018-12-11
    Sponsor Name:AZIENDA OSPEDALIERO-UNIVERSITARIA CAREGGI
    Full Title: Renal function evaluation through iohexol method in the elderly with sarcopenia and low serum creatinine
    Medical condition: Elderly sarcopenia patients with low serum creatinine and suspected chronic kidney disease
    Disease: Version SOC Term Classification Code Term Level
    21.1 100000004857 10009119 Chronic renal failure LLT
    20.1 10028395 - Musculoskeletal and connective tissue disorders 10063024 Sarcopenia PT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-005003-88 Sponsor Protocol Number: SIM15 Start Date*: 2016-03-15
    Sponsor Name:Cambridge University Hospitals NHS Foundation Trust and University of Cambridge
    Full Title: Survival Improvement with Cholecalciferol in Patients on Dialysis – The SIMPLIFIED Registry Trial
    Medical condition: Kidney Failure (requiring dialysis).
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000070575 10023420 Kidney failure chronic LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA)
    Trial results: (No results available)
    EudraCT Number: 2012-002744-24 Sponsor Protocol Number: 1058/12 Start Date*: 2012-12-16
    Sponsor Name:POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI
    Full Title: Effect of oral paricalcitol on endothelial function and FGF-23 in peritoneal dialysis patients: a pilot study
    Medical condition: CHRONIC RENAL FAILURE
    Disease: Version SOC Term Classification Code Term Level
    14.1 10038359 - Renal and urinary disorders 10038444 Renal failure chronic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-003081-32 Sponsor Protocol Number: 1160.166 Start Date*: 2012-04-18
    Sponsor Name:Boehringer Ingelheim bv
    Full Title: An exploratory study to investigate the pharmacokinetics and effects of DABIgatran etexilate in patients with stable severe RENAL disease: DabiRenal
    Medical condition: Chronic kidney disease and coagulation
    Disease: Version SOC Term Classification Code Term Level
    15.0 10022891 - Investigations 10060318 Anticoagulation drug level PT
    15.0 10038359 - Renal and urinary disorders 10038444 Renal failure chronic PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2011-006168-30 Sponsor Protocol Number: RLH_Pentoxifylline_Dec2011 Start Date*: 2013-01-08
    Sponsor Name:R&D, Barts and The London NHS Trust
    Full Title: PEntoxifylline in Anaemia Resistant to erythropoietin (PEAR)
    Medical condition: We shall study patients with renal failure on dialysis. We shall particularly focus on patients with evidence of erythopoeitin stimulating agent (ESA) resistance.
    Disease: Version SOC Term Classification Code Term Level
    14.1 100000004857 10014647 End stage renal failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: GB (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2010-020114-29 Sponsor Protocol Number: IGFHD1-2010 Start Date*: 2010-07-13
    Sponsor Name:Department of Nephrology
    Full Title: Insulin-like growth factor in hemodialysis patients
    Medical condition: This project aims to investigate whether the anabolic potentials of insulin may be used to reverse the catabolic effects of hemodialysis in non-diabetic patients with end-stage renal failure. Thus...
    Disease: Version SOC Term Classification Code Term Level
    12.1 10014647 End stage renal failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2015-000856-16 Sponsor Protocol Number: DTG_HD Start Date*: 2015-05-27
    Sponsor Name:Fundació Lluita contra la SIDA
    Full Title: Removal of dolutegravir by hemodialysis in HIV-infected patients with end-stage renal disease.
    Medical condition: HIV-infected patients with end-stage renal disease
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004862 10068341 HIV-1 infection LLT
    17.1 100000004857 10014646 End stage renal disease (ESRD) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Completed)
    Trial results: View results
    EudraCT Number: 2022-000740-29 Sponsor Protocol Number: 270389-030122 Start Date*: 2022-04-12
    Sponsor Name:Department of Renal Medicine, Aarhus University Hospital
    Full Title: Sodium glucose cotransporter 2 inhibitors or Mineralocorticoid receptor antagonists for the treatment of Albuminuric Chronic Kidney Disease - A randomized controlled trial
    Medical condition: Chronic Kidney Disease with albuminuria
    Disease: Version SOC Term Classification Code Term Level
    23.1 10038359 - Renal and urinary disorders 10064848 Chronic kidney disease PT
    20.0 10038359 - Renal and urinary disorders 10001580 Albuminuria PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: View results
    EudraCT Number: 2008-001200-23 Sponsor Protocol Number: CCFM 103/208 Start Date*: 2008-07-13
    Sponsor Name:FONDAZIONE MONZINO CENTRO CARDIOLOGICO
    Full Title: A Study to Evaluate the Effectiveness of Induced Diuresis with Matched Hydration Therapy Compared to Standard Overnight Hydration in the Prevention of Contrast Induced Nephropathy
    Medical condition: Patients with moderate to severe renal failure candidates to angiographic procedures at high risk for CIN
    Disease: Version SOC Term Classification Code Term Level
    9.1 10009119 Chronic renal failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Completed)
    Trial results: View results
    EudraCT Number: 2006-001407-11 Sponsor Protocol Number: Certican MHH PRTx01 Start Date*: 2006-07-18
    Sponsor Name:Medizinische Hochschule Hannover
    Full Title: A single center study investigating ciclosporine A microemulsion in combination with basiliximab and prednisolon and switch to low-dose ciclosporine A and everolimus without steroids in the prevent...
    Medical condition: Kidney transplantation after end stage renal failure
    Disease: Version SOC Term Classification Code Term Level
    9.0 10014647 LLT
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: DE (Completed)
    Trial results: View results
    EudraCT Number: 2012-000948-98 Sponsor Protocol Number: H-3-2011-154 Start Date*: 2012-05-03
    Sponsor Name:Rigshospitalet
    Full Title: Effect of epinephrine on systemic absorption of mepivacaine administered for brachial plexus block in patients with end-stage renal disease
    Medical condition: End-stage renal disease
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004857 10014646 End stage renal disease (ESRD) LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2014-003496-29 Sponsor Protocol Number: I13034 Start Date*: 2014-10-24
    Sponsor Name:University Hospital, Limoges
    Full Title: Designing a Bayesian model of the plasma clearance of Calcium edetate de sodium, with a limited sampling strategy for the calculation of Glomerular Filtration Rate (GFR) and validity assessment com...
    Medical condition: Chronic Kidney Disease
    Disease: Version SOC Term Classification Code Term Level
    17.1 100000004857 10064848 Chronic kidney disease LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: FR (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2008-006014-20 Sponsor Protocol Number: FARM6X822T Start Date*: 2009-01-19
    Sponsor Name:CONSORZIO MARIO NEGRI SUD
    Full Title: Effects of the dose of erythropoiesis stimulating agents on cardiac-cerebrovascular outcomes and quality of life in hemodialysis patients. The DOSe of Erythropoietins (DOSE) trial.
    Medical condition: End stage kidney disease and anemia, treated with hemodialysis for renal replacement therapy
    Disease: Version SOC Term Classification Code Term Level
    9.1 10014647 End stage renal failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
    As of 31 January 2023, all EU/EEA initial clinical trial applications must be submitted through CTIS . Updated EudraCT trials information and information on PIP/Art 46 trials conducted exclusively in third countries continues to be submitted through EudraCT and published on this website.

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